Reference Digest of Biology Research with SPM

This section contains a collection of SPM related Annual Meeting Abstracts from the Biophysical Journal. The publications below can be found on the journal website

The titles at our opinion reflect the mainstream of today's activities of biologists exploiting the Scanning Probe Microscopy methods and techniques in their studies.

Please, send all comments and suggestions concerning these pages to

Biophysics Journal (Annual Meeting Abstracts), 80 (2001) January Page
Atomic force microscopy studies of three-way DNA junctions
Y.L. Lyubchenko, L. Shlyakhtenko, R. Sinden, V.N. Potaman, and A. Gall
Scanning probe microscopy study of myosin binding, topography and elastic properties of thin nitrocellulose films
A. Mansson, J. Klinth, E. Johansson-Karlsson, C. Widen, J. Johansson, and L. Montelius
Stepwise unfolding of titin under force-clamp AFM
A.F. Oberhauser, P.K. Hansma, M. Carrion-Vazquez, and J.M. Fernandez
Two-state model of polysaccharide elasticity probed with the force clamp mode of AFM
P.E. Marszalek, A.F. Oberhauser, and J.M. Fernandez
A combined atomic force, confocal, and total internal reflection microscope for the study of single molecules
W.F. Heinz, B. Navarro, K.D. Weston, P. Bernardi, and L.S. Goldner
Fingerprinting polysaccharides with single molecule atomic force microscopy
P.E. Marszalek, H. Li, and J.M. Fernandez
Single molecule interaction of receptors and antibodies with human rhinovirus HRV2 using AFM
F. Kienberger, R. Moser, C. Riener, H.J. Gruber, H. Schindler, D. Blaas, and P. Hinterdorfer
Thermal study of the adenovirus structure using differential scanning calorimetry and atomic force microscope
A. Negishi, G. Mattews, D. McCarty, J. Samulski, R. Taylor, and R. Superfine
The high-speed AFM and motion pictures
T. Ando, D. Maruyama, K. Saito, and T. Toda
Determination of elastic moduli of soft, thin samples using the atomic force microscope
E.K. Dimitriadis, F. Horkay, J. Maresca, and R.S. Chadwick
Atomic force microscopy studies of membrane structure and transformation thermodynamics
F. Tokumasu, A.J. Jin, and J.A. Dvorak
Novel cantilever design for atomic force microscopy
K. Snyder, A. Beyder, and F. Sachs
Identification of stress fibres and fibronectin in AFM images using confocal microscopy
K.L. De Jong, N.O. Petersen, and P.R. Norton
Hyphae hot off the presses: investigating cell wall structure by atomic force microscopy
L.A. Snook, S.J. Kaminskyj, and T.E.S. Dahms
Cellular mechanotransduction and its modulation: an atomic force microscopy study
G. Charras and M.A. Horton
Electromotility of hek cells measured with AFM
P.C. Zhang, A.M. Keleshian, and F. Sachs
Viscoelastic and active response of neuronal growth cones to mechanical stimuli by AFM
M. Lakadamyali, R. Mahaffy, B. Furnish, J. Bayer, F. Mackintosh, C.K. Shih, C. Schmidt, and J. Kas
Combining atomic force microscopy and patch clamp in cochlear outer hair cells
J.F. Ashmore, G. Charras, and M.A. Horton
AFM of DNA: a practical procedure for sample imaging under dry nitrogen
T.B.L. Kist, L.T.C. Franca, and F.G. Yu
Tapping mode AFM of hyaluronan polysaccharide on mica in air: controlling the molecular extension
M.K. Cowman
Investigating the mechanical properties of individual fibrin fibers with the nanomanipulator AFM
M. Guthold
Lipid domain growth and shape changes as a function of temperature in binary lipid mixtures visualized by atomic force microscopy
C. Leidy, T. Kaasgaard, T.V. Ratto, M. Longo, O.G. Mouritsen, J.H. Crowe, and K. Jorgensen
Structural mapping of the insulin receptor by in situ scanning probe microscopy
A. Slade, J. Luh, S. Ho, and C.M. Yip
Electric field manipulation of single DNA molecules on microelectrodes studied by atomic force microscopy
J. van Noort, A. Storm, S. de Vries, and C. Dekker
Reca-DNA complex studied by atomic force microscopy
R. Kuroda, K. Umemura, M. Ishikawa, S. Ikawa, and T. Shibata
Controlled immobilization of DNA molecules using chemical modification of mica surfaces for atomic force microscopy
K. Umemura, M. Ishikawa, and R. Kuroda
Real time ripple phase formation in mica supported bilayers visualized by atomic force microscopy (AFM)
T. Kaasgaard, C. Leidy, O.G. Mouritsen, J.H. Crowe, and K. Jorgensen
AFM study of lipid bilayer compressibility
S.J. Crook and D.D. Busath
Relationship between lipid-bilayer organization and lateral lipid-ligand distribution investigated by atomic force microscopy
T. Kaasgaard, O.G. Mouritsen, and K. Jorgensen
Self-assembly of influenza hemagglutinin: studies of ectodomain aggegation by in situ atomic force microscopy
R.F. Epand, L.V. Chernomordik, C.M. Yip, D.L. LeDuc, Y.K. Shin, and R.M. Epand
Direct observation of lipid/protein interactions using atomic force microscopy on supported bilayers
A.S. Muresan and K.Y. Lee
In situ phospholipase A2 degradation of one- and two-component phospholipid bilayers imaged by atomic force microscopy
T. Kaasgaard, J.H. Ipsen, O.G. Mouritsen, and K. Jorgensen
Biophysics Journal (Annual Meeting Abstracts), 82 (2002) January Page
Molecular elasticity of single spectrin repeats studied by forced unfolding using AFM
S. M. Altmann, G. Raik, P. Lenne, J. Ylaenne, M. Nilges, H. J. K. Hoerber, and A. Rae
Chair-boat transitions in single polysaccharide molecules observed with force-clamp AFM
P. E. Marszalek, H. Li, A. F. Oberhauser, and J. M. Fernandez
Mechanical architecture of the tandem immunoglobulin regions of titin studied by single molecule AFM
H. Li, A. F. Oberhauser, W. A. Linke, M. Carrion Vazquez, and J. M. Fernandez
AFM and force spectroscopy of recombinant spider dragline silk protein nanofibers
E. M. Oroudjev and H. G. Hansma
A combined atomic force, confocal, and total internal reflection microscope for single molecule microscopy
W. F. Heinz, K. D. Weston, V. Jolivet, B. Navarro, P. Bernardi, and L. S. Goldner
Extraction of proteins from a living cell surface using AFM
R. Afrin and A. Ikai
Nano-mechanics of tertiary domains and cooperative secondary structure of proteins studied with atomic force microscope (AFM)
R. Hertadi, S. Koide, and A. Ikai
Direct measurement of protein dynamics by AFM
M. Osbourn, T. H. Oosterkamp, and T. Schmidt
Erythrocyte deformation in atomic force microscopy
A. L. Popescu Hategan, R. J. Law, and D. E. Discher
Fibronectin remodeling and integrin-containing structures studied by confocal microscopy and AFM
K. L. DeJong, P. R. Norton, and N. O. Petersen
Use of atomic force microscopy (AFM) to measure integrin - fibronectin (FN) adhesion force in vascular smooth muscle cells (VSM)
Z. Sun, U. Pohl, and G. A. Meininger
AFM and film balance investigations into the role of the membrane-associated lipopolysaccharide-binding protein (LBP)
S. Roes, T. Gutsmann, and U. Seydel
Combining atomic-force and two-photon fluorescence microscopy to investigate the architecture of the photosynthetic membrane
C. C. Gradinaru, S. T. Kafi, P. Martinsson, G. A. Blab, T. Schmidt, and T. J. Aartsma
Characterizing single molecules of the giant muscle protein titin with atomic force microscopy
K. Watanabe, C. Muhle Goll, M.S.Z. Kellermayer, S. Labeit, and H. L. Granzier
E-cadherin extra-cellular domain interaction examined by atomic force microscopy
R. G. Rudnitsky, F. Drees, W. J. Nelson, and T. W. Kenny
Local viscoelastic behavior and the impact on motility of normal and malignantly transformed fibroblasts using AFM
S. Park, D. Humphrey, R. Cardenas, Q. Chen, N. Peffley, C. Shih, and J. Kas
Issues concerning the measurement of elastic properties at microscopic scales with the AFM
E. K. Dimitriadis, F. Horkay, K. Bechara, and R. S. Chadwick
Visualization of the molecular and electronic structure of photosynthetic pigment-protein complexes with scanning probe microscopy
A. Stamouli, S. T. Kafi, A. J. Hoff, J.W.M. Frenken, T. H. Oosterkamp, and T. J. Aartsma
A combined approach of patch clamp and AFM for studying Ca2+ - dependent inactivation of class c-type Ca2+ channels
G. Roland, K.J.F. Kepplinger, R. Zhu, Y. Maulet, K. Groschner, N. M. Soldatov, P. Hinterdorfer, and C. Romanin
Atomic force microscopy study of the structure of single mucin molecules and their viscoelastic properties
G. Matthews, C. W. Davis, and R. C. Boucher
Monitoring immunoglobulin light chain amyloid fibril formation on surfaces using atomic force microscopy
A. L. Fink, M. Zhu, J. Li, and P. O. Souillac
Linking primary structure and biochemical function with protein conformation measured by scanning force microscopy
B. A. Todd, J. Rammohan, and S. J. Eppell
Changes in DNA tertiary structure following ditercalinium bis-intercalation observed by AFM
T. Berge, N. S. Jenkins, M. J. Waring, J. M. Edwardson, and R. M. Henderson
Nanoscopic lipid domain dynamics revealed by atomic force microscopy
F. Tokumasu, A. J. Jin, G. W. Feigenson, and J. A. Dvorak
Studies of phase transitions in supported bilayers of cationic and neutral lipids by simultaneous in situ fluorescence spectroscopy and atomic force microscopy
A. B. Fried, N. P. Plaskos, J. Luh, and C. M. Yip
Conformational dynamics in connexon structure at molecular resolution using coordinated atomic force (AFM) and electron microscopy (EM)
D. J. Muller, G. M. Hand, A. Engel, and G. E. Sosinsky
Reconstitution of the passive elasticity of muscle from single molecule AFM experiments
H. Li, W. A. Linke, A. F. Oberhauser, M. Carrion Vazquez, P. E. Marszalek, and J. M. Fernandez
Atomic force microscopy of biomolecular assembly at ordered interfaces
G. Yang and C. M. Yip
Visualisation of the streptavidin-biotin interaction using AFM
C. S. Neish, R. M. Henderson, and J. M. Edwardson
Atomic force microscopy imaging of structure and dynamics of intramolecular triplex DNA
Y. L. Lyubchenko, W. J. Tiner, A. Y. Lushnikov, V. N. Potaman, and R. R. Sinden
Real-time changes in mechanical properties of human endothelial cells upon Icam-1 crosslinking studied by atomic force microscopy
I. Kang, Q. Wang, C. M. Doerschuk, and R. E. Marchant
Enhanced dynamic range and sensitivity of protein arrays using gold probes and scanning electron microscopy
N. Levit Binnun, A. B. Lindner, and E. Moses
Simultaneous confocal-scanning probe microscopy imaging of cell surface phenomena
J. Shaw, K. Hodgson, and C. M. Yip
Crystals and cells as cores for polyelectrolyte nanocapsules studied by confocal, two-photon and atomic force microscopy
A. Diaspro, O. Cavalleri, S. Krol, D. Silvano, and A. Gliozzi
Collagen fibrillar constructs: new ideas on their formation and ultrastructure via a parallel AFM, TEM, ESI and NMR approach
A. C. Lin and M. Goh
Atomic force microscopy and fluorescence studies of lipid rafts in model membranes
L. J. Johnston, C. Yuan, P. Burgos, and J. Furlong
AFM investigation of elasticity and conformation maleability of single proteins and supramolecular structures
J. G. Forbes, K. Wang, and A. J. Jin
3d Surface Topograpghy, Ligand-Induced Conformational Changes And Aggregation Of Hemichannels: AFM Study Of Reconstituted Connexons
J. Thimm, H. Lin, and R. Lal
The structure of the platelet integrin aIIbbIII on model surfaces imaged by atomic force microscopy
M. A. Hussain and C. A. Siedlecki
New results on the microtopology of RNA ploymerase II using tapping mode atomic force microscopy in liquid
T. N. Rhodin, K. Umemura, M. Gad, S. Jarvis, M. Ishikawa, and J. Fu
Effects of mechanical stimulation of auditory mechano-sensory cells measured using atomic force microscopy
A. Zelenskaya, M. Radmacher, and M. Ulfendahl
Structural differences betweeen prepore and pore complexes of perfringolysin o identified by AFM
D. M. Czajkowsky, E. M. Hotze, R. K. Tweten, and Z. Shao
Expression of the human µ-opioid receptor in a stable Sf9 cell line for AFM and NSOM studies
L. A. Snook, D. R. Burns, D. Massotte, and TES. Dahms
Visualization of syntaxin by AFM
D. E. Saslowsky, J. Lawrence, R. M. Henderson, and J. M. Edwardson
Morphological changes induced by poloxamer P188 in phospholipid monolayers: an atomic force microscopy study
G. Wu
Structural charcterisation of a novel membrane protein, syncollin, with the atomic force microscope
N. A. Geisse, R. M. Henderson, and J. M. Edwardson